Integrating serum metabolomics and network analysis to explore the antidepressant activity of crocin in rats with chronic unexpected mild stress-induced depression

• Main Authors: Yan Luo (Author), Ziyan Zhong (Author), Huan Li (Author), Le Wang (Author), Dongwei Guo (Author), Xuanqi Dong (Author), Jian Liu (Author), Mingxia Xie (Author), Mei Wu (Author), Yun Xiang (Author), Xi Zhang (Author), Pan Meng (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AbstractContext Crocin exhibits anti-depressant properties. However, its underlying mechanisms and its relationship with metabolomics remain unclear.Objective This study elucidates the mechanism of action and potential targets of crocin in treating chronic unexpected mild stress (CUMS)-induced depre...