Bafetinib Suppresses the Transcription of PD-L1 Through c-Myc in Lung Cancer

Given the limitations of the existing antibody-based therapies, including immune-related adverse events, poor response rates, and intravenous route of dosing, small molecules inhibitors targeting PD-L1 are highly desirable. By cell-based screening, we found that tyrosine kinase inhibitor Bafetinib d...

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Main Authors: Xi Chen (Author), Qianqian Du (Author), Hongjie Guo (Author), Qiaojun He (Author), Bo Yang (Author), Ling Ding (Author)
Formato: Livro
Publicado em: Frontiers Media S.A., 2022-06-01T00:00:00Z.
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