Nucleoside Analog 2',3'-Isopropylidene-5-Iodouridine as Novel Efficient Inhibitor of HIV-1

• Main Authors: Ksenia Glumakova (Author), Georgy Ivanov (Author), Valeria Vedernikova (Author), Lena Shyrokova (Author), Timofey Lebedev (Author), Andrei Stomakhin (Author), Anastasia Zenchenko (Author), Vladimir Oslovsky (Author), Mikhail Drenichev (Author), Vladimir Prassolov (Author), Pavel Spirin (Author)
• Format: Book
• Published: MDPI AG, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nucleoside reverse transcriptase inhibitors are the first class of drugs to be approved by the FDA for the suppression of HIV-1 and are widely used for this purpose in combination with drugs of other classes. Despite the progress in HIV-1 treatment, there is still the need to develop novel efficient...