Exome genotyping and linkage analysis identifies two novel linked regions and replicates two others for myopia in Ashkenazi Jewish families

• Main Authors: Claire L. Simpson (Author), Anthony M. Musolf (Author), Qing Li (Author), Laura Portas (Author), Federico Murgia (Author), Roberto Y. Cordero (Author), Jennifer B. Cordero (Author), Bilal A. Moiz (Author), Emily R. Holzinger (Author), Candace D. Middlebrooks (Author), Deyana D. Lewis (Author), Joan E. Bailey-Wilson (Author), Dwight Stambolian (Author)
• Format: Book
• Published: BMC, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Myopia is one of most common eye diseases in the world and affects 1 in 4 Americans. It is a complex disease caused by both environmental and genetics effects; the genetics effects are still not well understood. In this study, we performed genetic linkage analyses on Ashkenazi Je...