Plasma biomarker analysis in pediatric ARDS: generating future framework from a pilot randomized control trial of methylprednisoloneA framework for identifying plasma biomarkers related to clinical outcomes in pediatric ARDS

• Main Authors: Dai eKimura (Author), Jordy eSaravia (Author), Cynthia R Rovnaghi (Author), Gianfranco Umberto Meduri (Author), Andreas eSchwingshackl (Author), Stephania eCormier (Author), Kanwaljeet J. S. Anand (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Lung injury activates multiple pro-inflammatory pathways, including neutrophils, epithelial and endothelial injury, and coagulation factors leading to acute respiratory distress syndrome (ARDS). Low-dose methylprednisolone therapy (MPT) improved oxygenation and ventilation in early pediat...