Delayed Mesoderm and Erythroid Differentiation of Murine Embryonic Stem Cells in the Absence of the Transcriptional Regulator FUBP1

• Autores principales: Josephine Wesely (Autor), Marlene Steiner (Autor), Frank Schnütgen (Autor), Manuel Kaulich (Autor), Michael A. Rieger (Autor), Martin Zörnig (Autor)
• Formato: Libro
• Publicado: Hindawi Limited, 2017-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

The transcriptional regulator far upstream binding protein 1 (FUBP1) is essential for fetal and adult hematopoietic stem cell (HSC) self-renewal, and the constitutive absence of FUBP1 activity during early development leads to embryonic lethality in homozygous mutant mice. To investigate the role of...