Identification of pharmacokinetic markers for safflower injection using a combination of system pharmacology, multicomponent pharmacokinetics, and quantitative proteomics study

• Autors principals: Peiying Shi (Autor), Yijun Ruan (Autor), Chenhui Zhong (Autor), Linglin Teng (Autor), Liyuan Ke (Autor), Hong Yao (Autor)
• Format: Llibre
• Publicat: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Safflower injection (SI), a water-extract preparation from safflower (Carthamus tinctorius L.), has been widely used for the treatment of cardio-cerebrovascular diseases. This work aims to develop an approach for identifying PK markers of cardiovascular herbal medicines using SI as a case study. Fir...