Whole genome sequencing of field isolates reveals a common duplication of the Duffy binding protein gene in Malagasy Plasmodium vivax strains.

• Main Authors: Didier Menard (Author), Ernest R Chan (Author), Christophe Benedet (Author), Arsène Ratsimbasoa (Author), Saorin Kim (Author), Pheaktra Chim (Author), Catherine Do (Author), Benoit Witkowski (Author), Remy Durand (Author), Marc Thellier (Author), Carlo Severini (Author), Eric Legrand (Author), Lise Musset (Author), Bakri Y M Nour (Author), Odile Mercereau-Puijalon (Author), David Serre (Author), Peter A Zimmerman (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Plasmodium vivax is the most prevalent human malaria parasite, causing serious public health problems in malaria-endemic countries. Until recently the Duffy-negative blood group phenotype was considered to confer resistance to vivax malaria for most African ethnicities. We and others have reported t...