B-1a cells protect mice from sepsis-induced acute lung injury

• Main Authors: Monowar Aziz (Author), Yasumasa Ode (Author), Mian Zhou (Author), Mahendar Ochani (Author), Nichol E. Holodick (Author), Thomas L. Rothstein (Author), Ping Wang (Author)
• Format: Book
• Published: BMC, 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Sepsis morbidity and mortality are aggravated by acute lung injury (ALI) or acute respiratory distress syndrome (ARDS). Mouse B-1a cells are a phenotypically and functionally unique sub-population of B cells, providing immediate protection against infection by releasing natural a...