Quantification of 15 Antibiotics Widely Used in the Critical Care Unit with a LC-MS/MS System: An Easy Method to Perform a Daily Therapeutic Drug Monitoring

• Main Authors: Catherine Feliu (Author), Celine Konecki (Author), Tristan Candau (Author), Damien Vautier (Author), Cyril Haudecoeur (Author), Claire Gozalo (Author), Yoann Cazaubon (Author), Zoubir Djerada (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Potential under- or overdose of antibiotics may occur in intensive care units due to high variability in plasma concentrations. The risk is either treatment failure or toxicity. Thus, therapeutic drug monitoring of antibiotics may guide dosing adjustment, maximising antibacterial efficacy and minimi...