The effect of azithromycin on ivermectin pharmacokinetics--a population pharmacokinetic model analysis.

• Main Authors: Ahmed El-Tahtawy (Author), Paul Glue (Author), Emma N Andrews (Author), Jack Mardekian (Author), Guy W Amsden (Author), Charles A Knirsch (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2008-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: A recent drug interaction study reported that when azithromycin was administered with the combination of ivermectin and albendazole, there were modest increases in ivermectin pharmacokinetic parameters. Data from this study were reanalyzed to further explore this observation. A compartme...