Mutation spectrum of 122 hemophilia A families from Taiwanese population by LD-PCR, DHPLC, multiplex PCR and evaluating the clinical application of HRM

• المؤلفون الرئيسيون: Chang Chieh-Ting (مؤلف), Chiou Shyh-Shin (مؤلف), Tsay Woei (مؤلف), Hung Chia-Cheng (مؤلف), Su Yi-Ning (مؤلف), Lin Shin-Yu (مؤلف), Ho Hong-Nerng (مؤلف), Lee Chien-Nan (مؤلف)
• التنسيق: كتاب
• منشور في: BMC, 2008-06-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Hemophilia A represents the most common and severe inherited hemorrhagic disorder. It is caused by mutations in the F8 gene, which leads to a deficiency or dysfunctional factor VIII protein, an essential cofactor in the factor X acti...