Rapid Determination of 9 Tyrosine Kinase Inhibitors for the Treatment of Hepatocellular Carcinoma in Human Plasma by QuEChERS-UPLC-MS/MS

• Egile Nagusiak: Wen Jiang (Egilea), Tingting Zhao (Egilea), Xiaolan Zhen (Egilea), Chengcheng Jin (Egilea), Hui Li (Egilea), Jing Ha (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

A reliable and rapid method employing QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) pretreatment coupled with ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) was successfully developed and validated for the analysis of nine tyrosine kinase inhibitors (TKIs)...