Design and Synthesis of Novel 5-((3-(Trifluoromethyl)piperidin-1-yl)sulfonyl)indoline-2,3-dione Derivatives as Promising Antiviral Agents: In Vitro, In Silico, and Structure-Activity Relationship Studies

• Autori principali: Rogy R. Ezz Eldin (Autore), Marwa A. Saleh (Autore), Sefat A. Alwarsh (Autore), Areej Rushdi (Autore), Azza Ali Althoqapy (Autore), Hoda S. El Saeed (Autore), Ayman Abo Elmaaty (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2023-09-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Herein, a series of new isatin derivatives was designed and synthesized (<b>1</b>-<b>9</b>) as broad-spectrum antiviral agents. Consequently, the antiviral activities of the synthesized compounds (<b>1</b>-<b>9</b>) were pursued against three viruses,...