Amphotericin B resistance in Leishmania amazonensis: In vitro and in vivo characterization of a Brazilian clinical isolate.

• Main Authors: Bianca A Ferreira (Author), Elizabeth M Coser (Author), Stephane de la Roca (Author), Juliana I Aoki (Author), Nilson Branco (Author), Gustavo H C Soares (Author), Mayara I S Lima (Author), Adriano C Coelho (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In Brazil, Leishmania amazonensis is the etiological agent of cutaneous and diffuse cutaneous leishmaniasis. The state of Maranhão in the Northeast of Brazil is prevalent for these clinical forms of the disease and also has high rates of HIV infection. Here, we characterized the drug susceptibility...