4-Heteroaryl Substituted Amino-3,5-Dicyanopyridines as New Adenosine Receptor Ligands: Novel Insights on Structure-Activity Relationships and Perspectives

• मुख्य लेखकों: Daniela Catarzi (लेखक), Flavia Varano (लेखक), Erica Vigiani (लेखक), Sara Calenda (लेखक), Fabrizio Melani (लेखक), Katia Varani (लेखक), Fabrizio Vincenzi (लेखक), Silvia Pasquini (लेखक), Natascia Mennini (लेखक), Giulia Nerli (लेखक), Diego Dal Ben (लेखक), Rosaria Volpini (लेखक), Vittoria Colotta (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

A new set of amino-3,5-dicyanopyridines was synthesized and biologically evaluated at the adenosine receptors (ARs). This chemical class is particularly versatile, as small structural modifications can influence not only affinity and selectivity, but also the pharmacological profile. Thus, in order...