Melanoma Brain Metastases Patient-Derived Organoids: An In Vitro Platform for Drug Screening

• मुख्य लेखकों: Saif-Eldin Abedellatif (लेखक), Racha Hosni (लेखक), Andreas Waha (लेखक), Gerrit H. Gielen (लेखक), Mohammed Banat (लेखक), Motaz Hamed (लेखक), Erdem Güresir (लेखक), Anne Fröhlich (लेखक), Judith Sirokay (लेखक), Anna-Lena Wulf (लेखक), Glen Kristiansen (लेखक), Torsten Pietsch (लेखक), Hartmut Vatter (लेखक), Michael Hölzel (लेखक), Matthias Schneider (लेखक), Marieta Ioana Toma (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2024-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background and aims: Brain metastases are prevalent in the late stages of malignant melanoma. Multimodal therapy remains challenging. Patient-derived organoids (PDOs) represent a valuable pre-clinical model, faithfully recapitulating key aspects of the original tumor, including the heterogeneity and...