Melanoma Brain Metastases Patient-Derived Organoids: An In Vitro Platform for Drug Screening

Background and aims: Brain metastases are prevalent in the late stages of malignant melanoma. Multimodal therapy remains challenging. Patient-derived organoids (PDOs) represent a valuable pre-clinical model, faithfully recapitulating key aspects of the original tumor, including the heterogeneity and...

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Main Authors: Saif-Eldin Abedellatif (Author), Racha Hosni (Author), Andreas Waha (Author), Gerrit H. Gielen (Author), Mohammed Banat (Author), Motaz Hamed (Author), Erdem Güresir (Author), Anne Fröhlich (Author), Judith Sirokay (Author), Anna-Lena Wulf (Author), Glen Kristiansen (Author), Torsten Pietsch (Author), Hartmut Vatter (Author), Michael Hölzel (Author), Matthias Schneider (Author), Marieta Ioana Toma (Author)
Format: Book
Published: MDPI AG, 2024-08-01T00:00:00Z.
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