Immunohistochemical, pharmacovigilance, and omics analyses reveal the involvement of ATP-sensitive K+ channel subunits in cancers: role in drug-disease interactions

• Main Authors: Fatima Maqoud (Author), Nicola Zizzo (Author), Marcella Attimonelli (Author), Antonella Tinelli (Author), Giuseppe Passantino (Author), Marina Antonacci (Author), Girolamo Ranieri (Author), Domenico Tricarico (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: ATP-sensitive-K+ channels (KATP) are involved in diseases, but their role in cancer is poorly described. Pituitary macroadenoma has been observed in Cantu' syndrome (C.S.), which is associated with the gain-of-function mutations of the ABCC9 and KCNJ8 genes. We tested the role of th...