Immunohistochemical, pharmacovigilance, and omics analyses reveal the involvement of ATP-sensitive K+ channel subunits in cancers: role in drug-disease interactions

• Principais autores: Fatima Maqoud (Autor), Nicola Zizzo (Autor), Marcella Attimonelli (Autor), Antonella Tinelli (Autor), Giuseppe Passantino (Autor), Marina Antonacci (Autor), Girolamo Ranieri (Autor), Domenico Tricarico (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2023-04-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Background: ATP-sensitive-K+ channels (KATP) are involved in diseases, but their role in cancer is poorly described. Pituitary macroadenoma has been observed in Cantu' syndrome (C.S.), which is associated with the gain-of-function mutations of the ABCC9 and KCNJ8 genes. We tested the role of th...