Immunohistochemical, pharmacovigilance, and omics analyses reveal the involvement of ATP-sensitive K+ channel subunits in cancers: role in drug-disease interactions

• Hoofdauteurs: Fatima Maqoud (Auteur), Nicola Zizzo (Auteur), Marcella Attimonelli (Auteur), Antonella Tinelli (Auteur), Giuseppe Passantino (Auteur), Marina Antonacci (Auteur), Girolamo Ranieri (Auteur), Domenico Tricarico (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2023-04-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Background: ATP-sensitive-K+ channels (KATP) are involved in diseases, but their role in cancer is poorly described. Pituitary macroadenoma has been observed in Cantu' syndrome (C.S.), which is associated with the gain-of-function mutations of the ABCC9 and KCNJ8 genes. We tested the role of th...