Stat1 Expression is an Independent Indicator of Prognosis in Lymph node Positive Breast Carcinomas
Introduction: STAT-1 is the main signal transducer of γIFN signalling through the IFGNR1. STAT-1 can act as a tumour suppressor by induction of the cycle inhibitors p27 and p21 and proapoptotic signals such as casapse 1. Both γIFN knockout mice and STAT-1 knockout mice show enhanced susceptibility t...
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Tehran University of Medical Sciences,
2005-03-01T00:00:00Z.
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