The Antidepressant-Like and Analgesic Effects of Kratom Alkaloids are accompanied by Changes in Low Frequency Oscillations but not ΔFosB Accumulation

• Main Authors: Shoshana Buckhalter (Author), Eric Soubeyrand (Author), Sarah A.E. Ferrone (Author), Duncan J. Rasmussen (Author), Joshua D. Manduca (Author), M. Sameer Al- (Author), Jude A. Frie (Author), Jibran Y. Khokhar (Author), Tariq A. Akhtar (Author), Melissa L. Perreault (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mitragyna speciosa ("kratom"), employed as a traditional medicine to improve mood and relieve pain, has shown increased use in Europe and North America. Here, the dose-dependent effects of a purified alkaloid kratom extract on neuronal oscillatory systems function, analgesia, and antidepre...