p53 status modifies cytotoxic activity of lactoferrin under hypoxic conditions

• Main Authors: Maryami Yuliana Kosim (Author), Takahiro Fukazawa (Author), Mutsumi Miyauchi (Author), Nobuyuki Hirohashi (Author), Keiji Tanimoto (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lactoferrin (LF) is an iron binding glycoprotein of the transferrin family with a wide spectrum of biological effects, including anti-cancer activity. However, the detailed molecular mechanisms of anti-cancer activity of LF have not been fully determined. In this study, we tried to clarify cytotoxic...