Preclinical Study of ZSP1273, a Potent Antiviral Inhibitor of Cap Binding to the PB2 Subunit of Influenza A Polymerase

• Main Authors: Xiaoxin Chen (Author), Qinhai Ma (Author), Manyu Zhao (Author), Yuqin Yao (Author), Qianru Zhang (Author), Miao Liu (Author), Zifeng Yang (Author), Wenbin Deng (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The influenza A virus is highly contagious and often causes global pandemics. The prevalence of strains of the influenza A virus that are resistant to approved drugs is a huge challenge for the current clinical treatment of influenza A. RNA polymerase is a pivotal enzyme in the replication of the in...