Polymorphism rs189037C > T in the promoter region of the ATM gene may associate with reduced risk of T2DM in older adults in China: a case control study

• Main Authors: Xiang Ding (Author), Qiukui Hao (Author), Ming Yang (Author), Tie Chen (Author), Shanping Chen (Author), Jirong Yue (Author), Sean X. Leng (Author), Birong Dong (Author)
• Formato: Livro
• Publicado em: BMC, 2017-08-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background Recent evidence indicates that ataxia telangiectasia mutated (ATM) is a cytoplasmic protein that involves in insulin signaling pathways. When ATM gene is mutated, this event appears to contribute to the development of insulin resistance and type 2 diabetes mellitus (T2DM). Up to...