Detection of Low-Level Fosfomycin-Resistant Variants by Decreasing Glucose-6-Phosphate Concentration in Fosfomycin Susceptibility Determination

• Autores principales: Guillermo Martín-Gutiérrez (Autor), Fernando Docobo-Pérez (Autor), Jose Manuel Rodríguez-Martínez (Autor), Alvaro Pascual (Autor), Jesús Blázquez (Autor), Jeronimo Rodriguez-Beltrán (Autor)
• Formato: Libro
• Publicado: MDPI AG, 2020-11-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Mutations that confer low-level fosfomycin resistance (LLFR) but not clinical resistance in <i>Escherichia coli</i> are increasingly reported. LLFR strains can become clinically resistant under urinary tract physiological conditions or may act as gateways for highly resistant subpopulati...