Detection of Low-Level Fosfomycin-Resistant Variants by Decreasing Glucose-6-Phosphate Concentration in Fosfomycin Susceptibility Determination

• Main Authors: Guillermo Martín-Gutiérrez (Author), Fernando Docobo-Pérez (Author), Jose Manuel Rodríguez-Martínez (Author), Alvaro Pascual (Author), Jesús Blázquez (Author), Jeronimo Rodriguez-Beltrán (Author)
• Format: Book
• Published: MDPI AG, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mutations that confer low-level fosfomycin resistance (LLFR) but not clinical resistance in <i>Escherichia coli</i> are increasingly reported. LLFR strains can become clinically resistant under urinary tract physiological conditions or may act as gateways for highly resistant subpopulati...