Detection of Low-Level Fosfomycin-Resistant Variants by Decreasing Glucose-6-Phosphate Concentration in Fosfomycin Susceptibility Determination

• Egile Nagusiak: Guillermo Martín-Gutiérrez (Egilea), Fernando Docobo-Pérez (Egilea), Jose Manuel Rodríguez-Martínez (Egilea), Alvaro Pascual (Egilea), Jesús Blázquez (Egilea), Jeronimo Rodriguez-Beltrán (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2020-11-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Mutations that confer low-level fosfomycin resistance (LLFR) but not clinical resistance in <i>Escherichia coli</i> are increasingly reported. LLFR strains can become clinically resistant under urinary tract physiological conditions or may act as gateways for highly resistant subpopulati...