Impact of obese levels on the hepatic expression of nuclear receptors and drug-metabolizing enzymes in adult and offspring mice

• Main Authors: Pei Wang (Author), Xueyan Shao (Author), Yifan Bao (Author), Junjie Zhu (Author), Liming Chen (Author), Lirong Zhang (Author), Xiaochao Ma (Author), Xiao-bo Zhong (Author)
• Format: Book
• Published: Elsevier, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The prevalence of obesity-associated conditions raises new challenges in clinical medication. Although altered expression of drug-metabolizing enzymes (DMEs) has been shown in obesity, the impacts of obese levels (overweight, obesity, and severe obesity) on the expression of DMEs have not been eluci...