Clearance of Apoptotic Cells by Macrophages Induces Regulatory Phenotype and Involves Stimulation of CD36 and Platelet-Activating Factor Receptor

Phagocytosis of apoptotic cells (efferocytosis) induces macrophage differentiation towards a regulatory phenotype (IL-10high/IL-12p40low). CD36 is involved in the recognition of apoptotic cells (AC), and we have shown that the platelet-activating factor receptor (PAFR) is also involved. Here, we inv...

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Autores principales: Matheus Ferracini (Autor), Francisco J. O. Rios (Autor), Mateus Pecenin (Autor), Sonia Jancar (Autor)
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Publicado: Hindawi Limited, 2013-01-01T00:00:00Z.
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