Clearance of Apoptotic Cells by Macrophages Induces Regulatory Phenotype and Involves Stimulation of CD36 and Platelet-Activating Factor Receptor

• Prif Awduron: Matheus Ferracini (Awdur), Francisco J. O. Rios (Awdur), Mateus Pecenin (Awdur), Sonia Jancar (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Hindawi Limited, 2013-01-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Phagocytosis of apoptotic cells (efferocytosis) induces macrophage differentiation towards a regulatory phenotype (IL-10high/IL-12p40low). CD36 is involved in the recognition of apoptotic cells (AC), and we have shown that the platelet-activating factor receptor (PAFR) is also involved. Here, we inv...