Muscle wasting in patients with end‐stage renal disease or early‐stage lung cancer: common mechanisms at work

• Main Authors: Julien Aniort (Author), Alexandre Stella (Author), Carole Philipponnet (Author), Anais Poyet (Author), Cécile Polge (Author), Agnès Claustre (Author), Lydie Combaret (Author), Daniel Béchet (Author), Didier Attaix (Author), Stéphane Boisgard (Author), Marc Filaire (Author), Eugénio Rosset (Author), Odile Burlet‐Schiltz (Author), Anne‐Elisabeth Heng (Author), Daniel Taillandier (Author)
• Format: Book
• Published: Wiley, 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Loss of muscle mass worsens many diseases such as cancer and renal failure, contributes to the frailty syndrome, and is associated with an increased risk of death. Studies conducted on animal models have revealed the preponderant role of muscle proteolysis and in particular the a...