P2Y2 receptor mediates dying cell removal via inflammatory activated microglia

• Main Authors: Izumi Hide (Author), Hiroko Shiraki (Author), Akihiro Masuda (Author), Takuya Maeda (Author), Mayuka Kumagai (Author), Nao Kunishige (Author), Yuhki Yanase (Author), Kana Harada (Author), Shigeru Tanaka (Author), Norio Sakai (Author)
• Format: Book
• Published: Elsevier, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Microglial removal of dying cells plays a beneficial role in maintaining homeostasis in the CNS, whereas under some pathological conditions, inflammatory microglia can cause excessive clearance, leading to neuronal death. However, the mechanisms underlying dying cell removal by inflammatory microgli...