Pharmacodynamic Evaluation of a Single Dose versus a 24-Hour Course of Multiple Doses of Cefazolin for Surgical Prophylaxis

• Príomhchruthaitheoirí: Aaron Heffernan (Údar), Jowana Alawie (Údar), Steven C Wallis (Údar), Saiyuri Naicker (Údar), Santosh Adiraju (Údar), Jason A. Roberts (Údar), Fekade Bruck Sime (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: MDPI AG, 2021-05-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

The optimal perioperative duration for the administration of cefazolin and other prophylactic antibiotics remains unclear. This study aimed to describe the pharmacodynamics of cefazolin for a single 2 g dose versus a 24 h course of a 2 g single dose plus a 1 g eight-hourly regimen against methicilli...