Preparation and release characteristics study on the novel minocycline hydrochloride sustained-release capsule

• Main Authors: Songfeng Zhao (Author), Xiao Zhang (Author), Xiaojian Zhang (Author), Xiuqin Shi (Author), Jun Li (Author), Quancheng Kan (Author), Shuoye Yang (Author)
• Format: Book
• Published: Bangladesh Pharmacological Society, 2016-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In present study, a novel minocycline hydrochloride sustained-release capsule was prepared with the new extrusion-spheronization method. The in vitro release studies were performed using marketed sample as a reference and data were analyzed in terms of cumulative release amounts as a function of tim...