Preclinical evaluation of CXCR4 peptides for targeted radionuclide therapy in glioblastoma

• Autores principales: Anthony Waked (Autor), Melissa Crabbé (Autor), Virginie Neirinckx (Autor), Sunay Rodriguez Pérez (Autor), Jasmien Wellens (Autor), Bernard Rogister (Autor), M. Abderrafi Benotmane (Autor), Koen Vermeulen (Autor)
• Formato: Libro
• Publicado: SpringerOpen, 2024-07-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Abstract Background Glioblastoma (GBM), is the most fatal form of brain cancer, with a high tendency for recurrence despite combined treatments including surgery, radiotherapy, and chemotherapy with temozolomide. The C-X-C chemokine receptor 4 (CXCR4) plays an important role in tumour radioresistanc...