Sex-Associated Differential mRNA Expression of Cytokines and Its Regulation by Sex Steroids in Different Brain Regions in a Plasmodium berghei ANKA Model of Cerebral Malaria

• Main Authors: Martha Legorreta-Herrera (Author), Karen E. Nava-Castro (Author), Margarita I. Palacios-Arreola (Author), Rosalía Hernández-Cervantes (Author), Jesús Aguilar-Castro (Author), Luis A. Cervantes-Candelas (Author), Jorge Morales-Montor (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cerebral malaria (CM) is the major complication associated with death in malaria patients, and its pathogenesis is associated with excessive proinflammatory cytokine production. Notably, the severity and mortality of natural infections with Plasmodium are higher in males than females, suggesting tha...