Novel Peripherally Restricted Cannabinoid 1 Receptor Selective Antagonist TXX-522 with Prominent Weight-Loss Efficacy in Diet Induced Obese Mice
The clinical development of the first generation of globally active cannabinoid 1 receptor (CB1R) antagonists was suspended because of their adverse neuropsychiatric effects. Selective blockade of peripheral CB1Rs has the potential to provide a viable strategy for the treatment of severe obesity whi...
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Main Authors: | , , , , , , , |
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Format: | Book |
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Frontiers Media S.A.,
2017-10-01T00:00:00Z.
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A1234.567 |
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Copy 1 | Available |