The glutamine synthetase of Trypanosoma cruzi is required for its resistance to ammonium accumulation and evasion of the parasitophorous vacuole during host-cell infection.

• المؤلفون الرئيسيون: Marcell Crispim (مؤلف), Flávia Silva Damasceno (مؤلف), Agustín Hernández (مؤلف), María Julia Barisón (مؤلف), Ismael Pretto Sauter (مؤلف), Raphael Souza Pavani (مؤلف), Alexandre Santos Moura (مؤلف), Elizabeth Mieko Furusho Pral (مؤلف), Mauro Cortez (مؤلف), Maria Carolina Elias (مؤلف), Ariel Mariano Silber (مؤلف)
• التنسيق: كتاب
• منشور في: Public Library of Science (PLoS), 2018-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Trypanosoma cruzi, the etiological agent of Chagas disease, consumes glucose and amino acids depending on the environmental availability of each nutrient during its complex life cycle. For example, amino acids are the major energy and carbon sources in the intracellular stages of the T. cruzi parasi...