Discrete Element Method Evaluation of Triboelectric Charging Due to Powder Handling in the Capsule of a DPI

• Prif Awduron: Francesca Orsola Alfano (Awdur), Alberto Di Renzo (Awdur), Francesco Paolo Di Maio (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: MDPI AG, 2023-06-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

The generation and accumulation of an electrostatic charge from handling pharmaceutical powders is a well-known phenomenon, given the insulating nature of most APIs (Active Pharmaceutical Ingredients) and excipients. In capsule-based DPIs (Dry Powder Inhalers), the formulation is stored in a gelatin...