Noncoding RNA Transcripts during Differentiation of Induced Pluripotent Stem Cells into Hepatocytes

• Hauptverfasser: Aniela Skrzypczyk (VerfasserIn), Stephanie Kehr (VerfasserIn), Ilona Krystel (VerfasserIn), Stephan H. Bernhart (VerfasserIn), Shibashish Giri (VerfasserIn), Augustinus Bader (VerfasserIn), Peter F. Stadler (VerfasserIn)
• Format: Buch
• Veröffentlicht: Hindawi Limited, 2018-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Recent advances in the stem cell field allow to obtain many human tissues in vitro. However, hepatic differentiation of induced pluripotent stem cells (iPSCs) still remains challenging. Hepatocyte-like cells (HLCs) obtained after differentiation resemble more fetal liver hepatocytes. MicroRNAs (miRN...