Comparative analyses of response surface methodology and artificial neural networks on incorporating tetracaine into liposomes

• Ngā kaituhi matua: Ana Karina Vidal Pereira (Author), Raquel de Melo Barbosa (Author), Marcelo Augusto Costa Fernandes (Author), Leandro Finkler (Author), Christine Lamenha Luna Finkler (Author)
• Hōputu: Pukapuka
• I whakaputaina: Universidade de São Paulo, 2020-03-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

This study evaluated the incorporation of tetracaine into liposomes by RSM (Response Surface Methodology) and ANN (Artificial Neural Networks) based models. RCCD (rotational central composite design) and ANN were performed to optimize the sonication conditions of particles containing 100 % lipid. La...