Hydroxyethyl starch conjugates co-assembled nanoparticles promote photodynamic therapy and antitumor immunity by inhibiting antioxidant systems

• Main Authors: Xiang Chen (Author), Zhengtao Yong (Author), Yuxuan Xiong (Author), Hai Yang (Author), Chen Xu (Author), Xing Wang (Author), Qingyuan Deng (Author), Jiayuan Li (Author), Xiangliang Yang (Author), Zifu Li (Author)
• Format: Book
• Published: Elsevier, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Photodynamic therapy (PDT) can produce high levels of reactive oxygen species (ROS) to kill tumor cells and induce antitumor immunity. However, intracellular antioxidant systems, including glutathione (GSH) system and thioredoxin (Trx) system, limit the accumulation of ROS, resulting in compromised...