Genetic Variation in Autophagy-Related Genes Influences the Risk and Phenotype of Buruli Ulcer.

• Auteurs principaux: Carlos Capela (Auteur), Ange Dodji Dossou (Auteur), Rita Silva-Gomes (Auteur), Ghislain Emmanuel Sopoh (Auteur), Michel Makoutode (Auteur), João Filipe Menino (Auteur), Alexandra Gabriel Fraga (Auteur), Cristina Cunha (Auteur), Agostinho Carvalho (Auteur), Fernando Rodrigues (Auteur), Jorge Pedrosa (Auteur)
• Format: Livre
• Publié: Public Library of Science (PLoS), 2016-04-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Buruli ulcer (BU) is a severe necrotizing human skin disease caused by Mycobacterium ulcerans. Clinically, presentation is a sum of these diverse pathogenic hits subjected to critical immune-regulatory mechanisms. Among them, autophagy has been demonstrated as a cellular process of critical importan...