Dapagliflozin Alleviates Hepatic Steatosis by Restoring Autophagy via the AMPK-mTOR Pathway

• Main Authors: Liuran Li (Author), Qinghua Li (Author), Wenbin Huang (Author), Yibing Han (Author), Huiting Tan (Author), Min An (Author), Qianru Xiang (Author), Rui Zhou (Author), Li Yang (Author), Yanzhen Cheng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

As a newly approved oral hypoglycaemic agent, the sodium-glucose cotransporter 2 (SGLT2) inhibitor dapagliflozin, which is derived from the natural product phlorizin can effectively reduce blood glucose. Recent clinical studies have found that dapagliflozin alleviates non-alcoholic fatty liver disea...