STAT6 expression in T cells, alveolar macrophages and bronchial biopsies of normal and asthmatic subjects

• Main Authors: Tomita Katsuyuki (Author), Caramori Gaetano (Author), Ito Kazuhiro (Author), Sano Hiroyuki (Author), Lim Sam (Author), Oates Timothy (Author), Cosio Borja (Author), Chung K Fan (Author), Tohda Yuji (Author), Barnes Peter J (Author), Adcock Ian M (Author)
• Format: Book
• Published: BMC, 2012-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Asthma is characterised by increased numbers of Th2-like cells in the airways and IgE secretion. Generation of Th2 cells requires interleukin (IL)-4 and IL-13 acting through their specific receptors and activating the transcription f...