TLR7 Ligation Inhibits TLR8 Responsiveness in IL-27-Primed Human THP-1 Monocytes and Macrophages

• المؤلفون الرئيسيون: Natalya Odoardi (مؤلف), Olena Kourko (مؤلف), Carlene Petes (مؤلف), Sameh Basta (مؤلف), Katrina Gee (مؤلف)
• التنسيق: كتاب
• منشور في: Karger Publishers, 2021-05-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Regulation of proinflammatory cytokine expression is critical in the face of single-stranded RNA (ssRNA) virus infections. Many viruses, including coronavirus and influenza virus, wreak havoc on the control of cytokine expression, leading to the formation of detrimental cytokine storms. Understandin...