Peripheral Etanercept Administration Normalizes Behavior, Hippocampal Neurogenesis, and Hippocampal Reelin and GABAA Receptor Expression in a Preclinical Model of Depression

• Principais autores: Kyle J. Brymer (Autor), Erin Y. Fenton (Autor), Lisa E. Kalynchuk (Autor), Hector J. Caruncho (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2018-02-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Depression is a serious psychiatric disorder frequently comorbid with autoimmune disorders. Previous work in our lab has demonstrated that repeated corticosterone (CORT) injections in rats reliably increase depressive-like behavior, impair hippocampal-dependent memory, reduce the number and complexi...