Study of the potential toxicity of adrenaline to neurons, using the SH-SY5Y human cellular model

• Main Authors: Vera Marisa Costa (Author), João Paulo Capela (Author), Maria Lourdes Bastos (Author), Fernando Remião (Author), Kurt James Varner (Author), José Alberto Duarte (Author), Félix Carvalho (Author)
• Format: Book
• Published: Universidade de São Paulo, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Prolonged overexposure to catecholamines causes toxicity, usually credited to continuous adrenoceptor stimulation, autoxidation, and the formation of reactive pro-oxidant species. Non-differentiated SH-SY5Y cells were used to study the possible contribution of oxidative stress in adrenaline...