Granisetron-mediated augmentation of sertraline therapeutic effect in obsessive-compulsive disorder: a double-blind placebo-controlled, randomized clinical trial

• Main Authors: Ala Ghobadian (Author), Saba Mokhtari (Author), Behnam Shariati (Author), Leila Kamalzadeh (Author), Mohsen Shati (Author), Mehrdad Eftekhar Ardebili (Author), Masoomeh Yarahmadi (Author), Mohammadreza Shalbafan (Author)
• Format: Book
• Published: BMC, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Medications currently recommended for the treatment of Obsessive-Compulsive Disorder (OCD) usually relieve the severity of symptoms by as much as 20-30%, and satisfactory treatment is obtained in 40-60% of patients with OCD. Nevertheless, the remaining symptoms continue to impair...