Frameshift mutations of YPEL3 alter the sensory circuit function in Drosophila

• Main Authors: Jung Hwan Kim (Author), Monika Singh (Author), Geng Pan (Author), Adrian Lopez (Author), Nicholas Zito (Author), Benjamin Bosse (Author), Bing Ye (Author)
• Format: Book
• Published: The Company of Biologists, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A frameshift mutation in Yippee-like (YPEL) 3 was recently found from a rare human disorder with peripheral neurological conditions including hypotonia and areflexia. The YPEL gene family is highly conserved from yeast to human, but its members' functions are poorly defined. Moreover, the patho...