Low Expression of miR-466f-3p Sustains Epithelial to Mesenchymal Transition in Sonic Hedgehog Medulloblastoma Stem Cells Through Vegfa-Nrp2 Signaling Pathway

• Main Authors: Zein Mersini Besharat (Author), Claudia Sabato (Author), Agnese Po (Author), Francesca Gianno (Author), Luana Abballe (Author), Maddalena Napolitano (Author), Evelina Miele (Author), Felice Giangaspero (Author), Alessandra Vacca (Author), Giuseppina Catanzaro (Author), Elisabetta Ferretti (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

High-throughput analysis has improved the knowledge of medulloblastoma (MB), the leading cause of cancer related death in children, allowing a better comprehension of the key molecular pathways in MB pathogenesis. However, despite these advances, 30% of patients still die from the disease and surviv...