Delineation of the Exact Transcription Termination Signal for Type 3 Polymerase III

• Main Authors: Zongliang Gao (Author), Elena Herrera-Carrillo (Author), Ben Berkhout (Author)
• פורמט: ספר
• יצא לאור: Elsevier, 2018-03-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Type 3 Pol III promoters such as U6 are widely used for expression of small RNAs, including short hairpin RNA for RNAi applications and guide RNA in CRISPR genome-editing platforms. RNA polymerase III uses a T-stretch as termination signal, but the exact properties have not been thoroughly investiga...