Direct and Indirect Effect of Guselkumab on Anxiety, Depression, and Quality of Life in Patients with Moderate-to-Severe Plaque Psoriasis: A Mediation Analysis

• Main Authors: April W. Armstrong (Author), Peter Foley (Author), Yan Liu (Author), Megan Miller (Author), Rachel E. Teneralli (Author), Anthony Bewley (Author), Kenneth B. Gordon (Author), Kim A. Papp (Author), Chenglong Han (Author)
• Format: Book
• Published: Adis, Springer Healthcare, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Introduction Treating plaque psoriasis (PsO) with guselkumab (GUS) promotes skin clearance and is associated with improvements in health-related quality of life (HRQoL), anxiety, and depression. It is unclear whether improvements in patient-reported outcomes are due to resolution of skin sy...