Simultaneous enhancement of cellular and humoral immunity by the lymph node-targeted cholesterolized TLR7 agonist liposomes

• Main Authors: Dandan Wan (Author), Ziyi Bai (Author), Yu Zhang (Author), Li Chen (Author), Haiying Que (Author), Tianxia Lan (Author), Weiqi Hong (Author), Jiayu Huang (Author), Cai He (Author), Yuquan Wei (Author), Qiang Pu (Author), Xiawei Wei (Author)
• Format: Book
• Published: Elsevier, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Toll-like receptor (TLR) agonists, as promising adjuvants and immunotherapeutic agents, have the potential to enhance immune responses and modulate antigen-dependent T-cell immune memory through activation of distinct signaling pathways. However, their clinical application is hindered by uncontrolle...